What Is A TNF Receptor Associated Periodic Syndrome Or Disease?

March 22 22:11 2019 Print This Article

It is defined as a disorder in which there is a fever which occurs at periods. It is rare and genetic in nature. It is also known as the TRAPS. It leads to inflammation which cannot be controlled and involve many parts of the body. It occurs in the new born time and may lead to rashes, fever, as well as pain in the abdomen. It is in link with the cryopyrin. It occurs due to the mutations seen in the tumor necrosis factor. It was described in the Scottish boy in year 1982. It is also known as familial Hibernian fever.

What are the signs and symptoms of TNF receptor associated periodic syndrome or disease?

It includes the rashes, fever, as well as pain in the abdomen.

What are the causes of TNF receptor associated periodic syndrome or disease?

It includes the immune system which has macrophages. It occurs in response to infection and there is a activation of immune cells which starts the process of inflammation. Other causes are still under observation. The other reason is the incorrect shedding of TNF receptor. The mutations also affect the extra cellular domain of receptors.

How TNF receptor associated periodic syndrome or disease can be diagnosed?

It includes the medical history as well as the use of visual examination in the later stages.

How TNF receptor associated periodic syndrome or disease can be treated?

It can be treated with the help of a few medicines. It includes the use of anakirna, infliximab and tacrolimus. The studies which deal with the efficacy have not been updated yet.

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