What are the signs and symptoms of Acute myeloid leukemia?

March 07 22:18 2019 Print This Article

The symptoms of the disease are caused due to the replacement of bone marrow with the leukemic cells which decreases the red blood cells, platelets and normal white blood cells. It leads to fatigue, shortness of the breath, easy bruising and bleeding. There is also an increased chance of infection. There are many risk factors which can increase the AML but the exact cause is still not clear. It progresses rapidly and it may lead to the death of the individual within few months or weeks if not treated properly. The absence of platelets may lead to the bleeding or bruising.

The early signs of this disorder are vague and non specific. They are similar to influenza. It includes the fever, anemia, fatigue and the weight loss. There is also a loss of appetite and formation of petechiae which are flat and pin head size spots which are formed under the skin due to bleeding. It may also cause bone and joint pain and persistent infections. One can also observe the enlargement of spleen which can be asymptomatic and mild. One can hardly see the lymph node enlargement as it is seen in the ALL.

The involvement of the skin is around 10 percent and it occurs in the case of leukemia cutis. Sometimes one can see the presence of sweet syndrome which is the para neoplastic inflammation of the skin. One can also experience the swelling of gums as a result of the infiltration of leukemic cells into the gum tissue. The first sign of leukemia rarely occurs by the development of a solid leukemic mass or a tumor outside the bone marrow. It is referred as a chloroma. The person may show no symptoms accordingly and leukemia can be discovered by a routine blood test.

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