Pertussis

by andywalsh | December 22, 2019 9:24 pm

Whooping cough (pertussis) is a highly contagious disease marked by severe coughing. In the prevaccination era, pertussis (ie, whooping cough) was a leading cause of infant death. It is named after the “whoop” sound children and adults make when they try to breathe in during or after a severe coughing spell. There are 30-50 million cases per year, and about 300,000 deaths per year (World Health Organization data). Most deaths occur in children under one year of age.

Outbreaks of pertussis were first described in the 16th century, and the organism was first isolated in 1906. A respiratory infection characterized by paroxysmal coughing ending in a prolonged crowing intake of breath.The reasons for these increases are not entirely clear, but three- to five-year cycles of increased number of cases are known to occur. It is a serious bacterial infection of the lining of the breathing passages, particularly in the windpipe area. The germ is highly contagious and is easily spread from person to person.

B pertussis is a gram-negative pleomorphic bacillus that spreads via aerosolized droplets from coughing of infected individuals. B. pertussis produces multiple antigenic and biologically active products, including pertussis toxin, filamentous hemagglutinin, agglutinogens, adenylate cyclase, pertactin, and tracheal cytotoxin. Pertussis was recognizably described as early as 1578 by Guillaume de Baillou (1538-1616), but earlier reports date back at least to the 12th century.

Significant reductions in incidence and mortality have been achieved since the introduction of routine vaccination. Children with pertussis have decreased ability to cough up respiratory secretions and develop thick, glue-like mucus in the windpipe. Pertussis should be included in the differential diagnosis of protracted cough with cyanosis or vomiting, persistent rhinorrhea, and marked lymphocytosis.

Causes of Pertussis

The comman Causes of Pertussis include the following:

Symptoms of Pertussis

Some sign and symptoms related to Pertussis are as follows:

Treatment of Pertussis

Here is list of the methods for treating Pertussis:

Source URL: https://alldiseases.org/pertussis/