by andywalsh | December 22, 2019 9:23 pm

Pulmonary nocardiosis is an infection of the lung that is caused by the fungus-like bacteria Nocardia asteroides. Nocardia may also infect the skin through a cut or scratch that occurs while working outdoors or gardening. Nocardia are weakly gram-positive, filamentous bacteria found worldwide in soils. It occurs as sporadic cases worldwide. Some 70 cases, with about 20 deaths, occur per year in the USA.

The risk is greatly increased by immune suppression. If inhaled, the bacteria may cause pneumonia, which can lead to blood poisoning (sepsis) and the spread of nocardiosis to other organs of the body. This is called disseminated nocardiosis. majority (about 80%) of cases of nocardiosis involves lung infection, brain abscess, or disseminated (widespread) disease from Nocardia. Nocardiosis can be distinguished from actinomycosis by a lesser proclivity for sinus tract formation and a greater tendency for hematogenous dissemination specially to the brain.

Nocardiosis is found throughout the world among people of all ages, although it is most common in older people and males. Bronchopulmonary or disseminated nocardiosis can occure in various rheumatologic disease, including SLE, temporal arteritis, polyarthritis nodosa, intermittent hydarthrosis, vasculitis or uveitis. Nocardia brasiliensis is a common cause of localized chronic mycetoma.

Members of the genus Nocardia are aerobic actinomycetes that are ubiquitous saprophytes in soil, decaying organic matter, and water. Respiratory tract colonisation with Nocardia has been reported in patients with tuberculosis, asthma, bronchitis, aspergillosis and cancer. Nocardiosis is rare in AIDS patients. It is not transmitted by person-to-person contact. The diagnosis of Nocardia may be difficult. Newer molecular diagnostic and subtyping methods can assist in earlier diagnosis.

Causes of Nocardiosis

The comman causes of Nocardiosis include the following:

Symptoms of Nocardiosis

Some sign and symptoms related to Nocardiosis are as follows:

Treatment of Nocardiosis

Here is list of the methods for treating Nocardiosis:

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