What Is A Muckle Wells Syndrome Or Disease?

March 22 21:56 2019 Print This Article

It is defined as a disorder in which there is a rare autosomal dominant disease. It is also known as urticaria deafness amyloidosis. It is referred as the UDA. It leads to sensori neural deafness and there are recurrent hives. This condition can lead to amyloidosis. The patients with this disorder have chills, painful joints as well as fever. It is a type of periodic fever syndrome. It occurs due to the problem in gene due to the protein cryopyrin. It is related to other conditions also. These all are linked to the mutations and are known as cryo pyrin linked periodic symptoms.

What are the signs and symptoms of Muckle wells syndrome or disease?

It includes the chills, painful joints as well as fever. It is a type of periodic fever syndrome. It can also lead to painful joints as well as sensori neural deafness.

What are the causes of Muckle wells syndrome or disease?

It includes due to the problem in gene due to the protein cryopyrin. It is related to other conditions also. These all are linked to the mutations. The protein cryo pyrin responds to body infection as well as causes damage to the cells. A chemical known as interleukin 1 beta is produced by the immune cell which is known as macrophage. It has the ability to interact with a receptor on a surface present on other immune cells. The symptoms of inflammation like the fever, malaise as well as arthritis. The increase in activity of protein leads to increase the level of interleukin. It leads to inflammation in the body along with other symptoms.

How Muckle wells syndrome or disease can be treated?

It can be treated with the help of an anakirna which is a receptor antagonist. It improves the loss of hearing. One can also use fusion protein for the treatment of this disorder .One can also use a mono clonal antibody.

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