Kaposi’s sarcoma is a cancerous tumor of the connective tissue, and is often associated with AIDS. It is caused by Human Herpes Virus 8 in which cancerous cells, as well as abnormally growing blood vessels, form solid lesions in connective tissue. The most common site for KS is on the skin but it may also affect internal organs, particularly the lymph nodes (part of your immune system), the lungs and parts of the digestive system (the gut).
Kaposi sarcoma (KS) was named for Dr. Moritz Kaposi who first described it in 1872. It manifests in four distinct forms. The first form, called classic KS, was described by the Austrian dermatologist Moricz Kaposi more than a century ago. This condition carries a variable clinical course ranging from minimal mucocutaneous disease to extensive organ involvement. KS can occur in several different clinical settings. It is now the most frequent cancer to develop in people with AIDS, affecting about 20% overall. KS appears about eight times more often in gay men than in women. If isolated to the skin, KS is not life threatening.
KS is a spindle-cell tumor thought to be derived from endothelial cell lineage. KS was historically very rare and found mainly in older men of Mediterranean or African origin ( classic KS ) or patients with severely weakened immune systems, such as after an organ transplant. This disease typically causes tumors to develop in the tissues below the skin surface, or in the mucous membranes of the mouth, nose, or anus.
Most cancers, which start in one place and may then spread to other parts of the body, KS can appear in several parts of the body at the same time. It can appear as classic KS, or in a more deadly form that quickly spreads to tissues below the skin, the bones and lymph system, leading to death within a few years of diagnosis. In a recent study, men with HHV-8 were nearly 12 times more likely to be diagnosed with KS than men who did not have HHV-8. However, if KS forms in the intestinal track, lungs, brain or other internal organs, it can have serious consequences and can even be fatal.
The comman causes of Kaposi’s Sarcoma include the following:
Some sign and symptoms related to Kaposi’s Sarcoma are as follows:
Here is list of the methods for treating Kaposi’s Sarcoma:
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