What Is A Fatal Familial Insomnia Disease?

March 22 21:11 2019 Print This Article

It is defined as a disorder in which there is a rare disease of the brain. It occurs due to the mutation of the protein. It is also seen in the patients in whom there are no inherited mutations and is known as the sporadic fatal insomnia. It is known as the SFI. It is seen in less than 50 families worldwide. The parent with the gene of this disease has 50 percent of chances of their children to be infected. The patient is not able to sleep and it cannot be treated and can even lead to death.

What are the signs and symptoms of Fatal familial insomnia disease?

It includes the age ranging from 30 to 60. The average age is 50 and the disease occurs after the child birth. It also leads to death after 2 to 3 years of onset. The disease varies from one person to other and is even different in the same family.

The disease has 4 different stages:

It takes a year to run its course.

The stage one includes the patients suffering from insomnia. It results in panic attacks as well as phobia. It lasts for less than 6 months.

The stage two includes the panic attacks as well as hallucinations. It lasts for less than 6 months.

The stage third includes the full inability to sleep. There is a loss of weight too. It lasts for 3 months.

The stage four includes the dementia. The patient does not respond and becomes mute. It does not last for more than 6 months and may lead to death ultimately.

It may include increase in the sweating, pupils like pin prick and the entrance of women in the menopause. There is an impotency for the men, stiff neck, as well as increase in the heart rate and blood pressure. It can also lead to constipation.

What are the causes of Fatal familial insomnia disease?

It includes the genetic causes mainly. It is autosomal dominant. It involves the brain. There is mutation of the protein. It is also seen in the patients in whom there are no inherited mutations and is known as the sporadic fatal insomnia.

How Fatal familial insomnia disease can be treated?

It can be treated with the help of a gene therapy but the results are not satisfactory. The under lying cause must be reversed and it must have emphasis on the symptoms. It can improve the quality of life. But there is no cure for this disorder. The experiments on the mice are going on so that the treatment options can be explored.

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